BLNK antibody [5G9]

Catalogue Number: GTX60463-GTX

Manufacturer:	GeneTex
Preservative:	0.03% Sodium azide
Molecular Weight:	50
Physical state:	Liquid
Type:	Monoclonal Primary Antibody - Unconjugated
Alias:	B cell linker , AGM4 , BASH , BLNK-S , LY57 , SLP-65 , SLP65 , bca
Shipping Condition:	Blue Ice
Unit(s):	100 ul
Host name:	Mouse
Clone:	5G9
Isotype:	IgG1
Immunogen:	Purified recombinant fragment of human BLNK expressed in E. Coli.
Application:	ELISA, FC, ICC, IF, IHC-P, WB

Overview
Datasheets

Description

Description: This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, May 2012]

Additional Text

Gene ID

29760

Gene Name

BLNK

Uniprot ID

Q8WV28

Molecular Weight

Purification

Unpurified

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Application Notes

WB: 1/500 - 1/2000. ICC/IF: 1/200 - 1/1000. IHC-P: 1/200 - 1/1000. FCM: 1/200 - 1/400. ELISA: 1/10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

GTX60463 Datasheet

Price

£410.00

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Quantity
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