DLK1 antibody [3A10]

Catalogue Number: GTX60511-GTX

Manufacturer:GeneTex
Preservative:0.03% Sodium azide
Molecular Weight:41
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Alias:delta like non-canonical Notch ligand 1 , DLK , DLK-1 , Delta1 , FA1 , PREF1 , Pref-1 , ZOG , pG2
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Mouse
Clone: 3A10
Isotype: IgG1
Immunogen: Purified recombinant fragment of human DLK1 expressed in E. Coli.
Application: ELISA, FC, ICC, IF, WB, PLA

Description

Description: This gene encodes a transmembrane protein containing six epidermal growth factor repeats. The protein is involved in the differentiation of several cell types, including adipocytes; it is also thought to be a tumor suppressor. It is one of several imprinted genes located in a region of on chr 14q32. Certain mutations in this imprinted region can cause phenotypes similar to maternal and paternal uniparental disomy of chromosome 14 (UPD14). This gene is expressed from the paternal allele. A polymorphism within this gene has been associated with child and adolescent obesity. The mode of inheritance for this polymorphism is polar overdominance; this non-Mendelian inheritance pattern was first described in sheep with the callipyge phenotype, which is characterized by muscle hypertrophy and decreased fat mass. [provided by RefSeq, Mar 2010]

Additional Text

Gene Name

DLK1

Gene ID

8788

Purification

Unpurified

Uniprot ID

P80370

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Molecular Weight

41

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Application Notes

WB: 1/500 - 1/2000. ICC/IF: 1/200 - 1/1000. FCM: 1/200 - 1/400. ELISA: 1/10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.