LRP5 antibody [2B11]
Catalogue Number: GTX60567-GTX
GTX60567 Image
GTX60567 Image
GTX60567 Image
GTX60567 Image
ELISA analysis of antigen using GTX60567 LRP5 antibody [2B11]. Black : Control antigen 100ng Purple : Antigen 10ng Blue : Antigen 50ng Red : Antigen 100ng
GTX60567 Image
FACS analysis of HeLa cells using GTX60567 LRP5 antibody [2B11]. Green : LRP5 Red : negative control
GTX60567 Image
WB analysis of human LRP5 (AA: 1422-1615) recombinant protein using GTX60567 LRP5 antibody [2B11].
| Manufacturer: | GeneTex |
| Preservative: | 0.05% Sodium azide|0.05% Sodium azide |
| Molecular Weight: | 179 |
| Physical state: | Liquid |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | LDL receptor related protein 5 , BMND1 , EVR1 , EVR4 , HBM , LR3 , LRP-5 , LRP-7 , LRP7 , OPPG , OPS , OPTA1 , PCLD4 , VBCH2 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
| Host name: | Mouse |
| Clone: | 2B11 |
| Isotype: | IgG1 |
| Immunogen: | Purified recombinant fragment of human LRP5 expressed in E. Coli. |
| Application: | ELISA, FC, WB |
Description
Description: This gene encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]
Additional Text
Gene Name
LRP5
Uniprot ID
O75197
Purification
Protein G purified
Gene ID
4041
Molecular Weight
179
Antibody Clonality
Monoclonal
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Concentration
1 mg/ml
Storage Note
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Application Notes
WB: 1/500 - 1/2000. FCM: 1/200 - 1/400. ELISA: 1/10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
GTX60567 Datasheet
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