GLP1 antibody [10] (Biotin)
Catalogue Number: GTX60952-02-GTX
GTX60952-02 Image
GTX60952-02 Image
GTX60952-02 Image
The calibration curve of a sandwich assay for Non-amidated GLP-1 using GTX60954 as the capture antibody and GTX60952 -02 as the biotinylated detection antibody.
GTX60952-02 Image
This uses GTX60951 as capture antibody in combination with biotinylated detection antibody GTX60952 -02 exclusively to measure GLP-1(7-36)amide in biological samples. GLP-1(7-36)amide is the principal active form of the peptide, and has been estimated to make up about 70% of the physiological response. Relative to measuring both active forms of GLP-1 together, the responses are reduced by not measuring the approximately 30% contribution of GLP-1(7-37) to the overall response. There is no cross-reactivity with any extended or truncated physiological form of GLP-1(7-36)amide. Specimens must be collected into tubes containing an adequate amount of DPP-4 inhibitor (in addition to routine peptidase inhibitors) to prevent the rapid in vitro degradation of the active peptide.
| Manufacturer: | GeneTex |
| Preservative: | 15 mM Sodium azide |
| Molecular Weight: | 21 |
| Physical state: | Liquid |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Alias: | glucagon , GLP-1 , GLP1 , GLP2 , GRPP |
| Shipping Condition: | Blue Ice |
| Storage Condition: | 2-8°C |
| Unit(s): | 50 ul |
| Host name: | Mouse |
| Clone: | 10 |
| Isotype: | IgG2a |
| Immunogen: | Synthetic GLP-1(7-17) |
| Application: | ELISA |
Description
Description: The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon. [provided by RefSeq, Jul 2008]
Additional Text
Gene Name
GCG
Gene ID
2641
Uniprot ID
P01275
Antibody Clonality
Monoclonal
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Concentration
1 mg/ml
Storage Note
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4C.
GTX60952-02 Datasheet
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