Oct4 antibody [GT486]

Catalogue Number: GTX627419-GTX

Manufacturer:GeneTex
Preservative:No Preservative
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Alias:POU class 5 homeobox 1 , OCT3 , OCT4 , OTF-3 , OTF3 , OTF4 , Oct-3 , Oct-4
Shipping Condition:Blue Ice
Unit(s): 100 ul, 25 ul
Host name: Mouse
Clone: GT486
Isotype: IgG2a
Immunogen: Recombinant protein encompassing a sequence within the center region of human Oct4. The exact sequence is proprietary.
Application: FACS, ICC, IF, IHC-P, IP, WB

Description

Description: This gene encodes a transcription factor containing a POU homeodomain. This transcription factor plays a role in embryonic development, especially during early embryogenesis, and it is necessary for embryonic stem cell pluripotency. A translocation of this gene with the Ewing's sarcoma gene, t(6;22)(p21;q12), has been linked to tumor formation. Alternative splicing, as well as usage of alternative translation initiation codons, results in multiple isoforms, one of which initiates at a non-AUG (CUG) start codon. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12. [provided by RefSeq]

Additional Text

Gene ID

5460

Gene Name

POU5F1

Molecular Weight

39

Uniprot ID

Q01860

Concentration

1.66 mg/mL

Purification

Affinity Purified

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. FACS: 1:50-1:200. IP: 1:1000-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.