Fumarate hydratase antibody [GT7612]
Catalogue Number: GTX630146-GTX
| Manufacturer: | GeneTex |
| Preservative: | No Preservative |
| Physical state: | Liquid |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | fumarate hydratase , FMRD , HLRCC , LRCC , MCL , MCUL1 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul, 25 ul |
| Host name: | Mouse |
| Clone: | GT7612 |
| Isotype: | IgG3 |
| Immunogen: | Recombinant protein encompassing a sequence within the center region of human Fumarate hydratase. The exact sequence is proprietary. |
| Application: | ICC, IF, WB |
Description
Description: The protein encoded by this gene is an enzymatic component of the tricarboxylic acid (TCA) cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic form and an N-terminal extended form, differing only in the translation start site used. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension generates the same form as in the cytoplasm. It is similar to some thermostable class II fumarases and functions as a homotetramer. Mutations in this gene can cause fumarase deficiency and lead to progressive encephalopathy. [provided by RefSeq, Jul 2008]
Additional Text
Concentration
1 mg/ml
Gene Name
FH
Uniprot ID
P07954
Purification
Protein G purified
Gene ID
2271
Molecular Weight
55
Antibody Clonality
Monoclonal
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Application Notes
WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
GTX630146 Datasheet
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