TCP1 epsilon antibody [GT639]

Catalogue Number: GTX631668-GTX

Manufacturer:GeneTex
Preservative:No Preservative
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Alias:chaperonin containing TCP1 subunit 5 , CCT-epsilon , CCTE , HEL-S-69 , PNAS-102 , TCP-1-epsilon
Shipping Condition:Blue Ice
Unit(s): 100 ul, 25 ul
Host name: Mouse
Clone: GT639
Isotype: IgG1
Immunogen: Recombinant protein encompassing a sequence within the center region of human TCP1 epsilon. The exact sequence is proprietary.
Application: ICC, IF, IP, WB

Description

Description: The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Mutations in this gene cause hereditary sensory and autonomic neuropathy with spastic paraplegia (HSNSP). Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 5 and 13. [provided by RefSeq, Apr 2015]

Additional Text

Concentration

1 mg/ml

Gene Name

CCT5

Uniprot ID

P48643

Gene ID

22948

Purification

Protein G purified

Molecular Weight

60

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

WB: 1:500-1:3000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.