T-Plastin antibody [GT236]

Catalogue Number: GTX632481-GTX

Manufacturer:GeneTex
Preservative:No Preservative
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Alias:plastin 3 , BMND18 , T-plastin
Shipping Condition:Blue Ice
Unit(s): 100 ul, 25 ul
Host name: Mouse
Clone: GT236
Isotype: IgG1
Immunogen: Recombinant protein encompassing a sequence within the center region of human T-Plastin. The exact sequence is proprietary.
Application: IHC-P, WB

Description

Description: Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). The C-terminal 570 amino acids of the T-plastin and L-plastin proteins are 83% identical. It contains a potential calcium-binding site near the N terminus. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2010]

Additional Text

Concentration

1 mg/ml

Gene Name

PLS3

Uniprot ID

P13797

Purification

Protein G purified

Gene ID

5358

Molecular Weight

71

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.