beta Catenin antibody [GT3171]

Catalogue Number: GTX632676-GTX

Manufacturer:	GeneTex
Preservative:	No Preservative
Physical state:	Liquid
Type:	Monoclonal Primary Antibody - Unconjugated
Alias:	catenin beta 1 , CTNNB , EVR7 , MRD19 , armadillo
Shipping Condition:	Blue Ice
Unit(s):	100 ul, 25 ul
Host name:	Mouse
Clone:	GT3171
Isotype:	IgG1
Immunogen:	Recombinant protein encompassing a sequence within the N-terminus region of human beta Catenin. The exact sequence is proprietary.
Application:	ICC, IF, IHC-P, WB

Overview
Datasheets

Description

Description: Beta-catenin is an adherens junction protein. Adherens junctions (AJs; also called the zonula adherens) are critical for the establishment and maintenance of epithelial layers, such as those lining organ surfaces. AJs mediate adhesion between cells, communicate a signal that neighboring cells are present, and anchor the actin cytoskeleton. In serving these roles, AJs regulate normal cell growth and behavior. At several stages of embryogenesis, wound healing, and tumor cell metastasis, cells form and leave epithelia. This process, which involves the disruption and reestablishment of epithelial cell-cell contacts, may be regulated by the disassembly and assembly of AJs. AJs may also function in the transmission of the 'contact inhibition' signal, which instructs cells to stop dividing once an epithelial sheet is complete.[supplied by OMIM]

Additional Text

Gene Name

CTNNB1

Gene ID

1499

Concentration

1.18 mg/mL

Purification

Protein G purified

Uniprot ID

P35222

Molecular Weight

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

GTX632676 Datasheet

GTX632676 Reference

Price

£285.00

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