Catalogue Number: GTX634218-GTX
Manufacturer: | GeneTex |
Preservative: | No Preservative |
Physical state: | Liquid |
Type: | Monoclonal Primary Antibody - Unconjugated |
Alias: | Arginase 1 |
Shipping Condition: | Blue Ice |
Unit(s): | 100 ul, 25 ul |
Host name: | Mouse |
Clone: | GT5811 |
Isotype: | IgG2a |
Immunogen: | Full length human Arginase 1 recombinant protein. |
Application: | ELISA, FACS, IHC-P, sELISA, WB |
Description: Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform encoded by this gene, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia. [provided by RefSeq]
ARG1
383
P05089
Protein A purified
3.26 mg/ml
Monoclonal
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
35
WB: 1:500-1:3000. IHC-P: 1:100-1:1000. FACS: 1:50-1:200. ELISA: 1:1000-1:10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Arginase 1 antibody detects arginase 1, an enzyme with a predicted molecular weight of ~35 kDa. Arginase 1 is cytosolic and expressed primarily in hepatocytes, catalyzing the conversion of L-arginine to urea and L-ornithine. The activity of this enzyme has an immunoregulatory function in M2 macrophages.