VASP antibody [GT238]

Catalogue Number: GTX634448-GTX

Manufacturer:GeneTex
Preservative:No Preservative
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Alias:vasodilator stimulated phosphoprotein
Shipping Condition:Blue Ice
Unit(s): 100 ul, 25 ul
Host name: Mouse
Clone: GT238
Isotype: IgG2b
Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human VASP. The exact sequence is proprietary.
Application: ICC, IF, IHC-P, WB

Description

Description: Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG. [provided by RefSeq]

Additional Text

Concentration

1 mg/ml

Gene ID

7408

Gene Name

VASP

Uniprot ID

P50552

Purification

Protein A purified

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Molecular Weight

40

Application Notes

WB: 1:1000-1:10000. ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.