Vinculin antibody [GT3210]

Catalogue Number: GTX634535-GTX

Manufacturer:GeneTex
Preservative:No Preservative
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Alias:vinculin , CMD1W , CMH15 , HEL114 , MV , MVCL
Shipping Condition:Blue Ice
Unit(s): 100 ul, 25 ul
Host name: Mouse
Clone: GT3210
Isotype: IgG1
Immunogen: Recombinant protein encompassing a sequence within the center region of human Vinculin. The exact sequence is proprietary.
Application: IHC-P, WB

Description

Description: Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008]

Additional Text

Gene Name

VCL

Uniprot ID

P18206

Concentration

1 mg/ml

Gene ID

7414

Purification

Protein G purified

Molecular Weight

124

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

WB: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.