PKM antibody [GT1810]

Catalogue Number: GTX634796-GTX

Manufacturer:GeneTex
Preservative:No Preservative
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Alias:pyruvate kinase M1/2 , CTHBP , HEL-S-30 , OIP3 , PK3 , PKM2 , TCB , THBP1
Shipping Condition:Blue Ice
Unit(s): 100 ul, 25 ul
Host name: Mouse
Clone: GT1810
Isotype: IgG1
Immunogen: Recombinant protein encompassing a sequence within the center region of human PKM. The exact sequence is proprietary.
Application: ICC, IF, IHC-P, WB

Description

Description: This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Several alternatively spliced transcript variants encoding a few distinct isoforms have been reported. [provided by RefSeq, May 2011]

Additional Text

Gene Name

PKM

Gene ID

5315

Uniprot ID

P14618

Purification

Protein G purified

Molecular Weight

58

Concentration

1.43 mg/ml

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

WB: 1:1000-1:10000. ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.