Iba1 antibody [HL22]
Catalogue Number: GTX635363-GTX
| Manufacturer: | GeneTex |
| Preservative: | No Preservative |
| Physical state: | Liquid |
| Type: | Recombinant Monoclonal |
| Alias: | allograft inflammatory factor 1 , AIF-1 , IBA1 , IRT-1 , IRT1 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul, 25 ul |
| Host name: | Rabbit |
| Clone: | HL22 |
| Isotype: | IgG |
| Immunogen: | Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Iba1. The exact sequence is proprietary. |
| Application: | ICC, IF, IHC-P, WB, IHC-Fr |
Description
Description: This gene encodes a protein that binds actin and calcium. This gene is induced by cytokines and interferon and may promote macrophage activation and growth of vascular smooth muscle cells and T-lymphocytes. Polymorphisms in this gene may be associated with systemic sclerosis. Alternative splicing results in multiple transcript variants, but the full-length and coding nature of some of these variants is not certain. [provided by RefSeq, Jan 2016]
Additional Text
Concentration
1 mg/ml
Uniprot ID
P55008
Gene Name
AIF1
Gene ID
199
Purification
Protein A purified
Antibody Clonality
Recombinant Monoclonal
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Molecular Weight
17
Application Notes
WB: 1:500-1:3000. IHC-P: 1:100-1:1000. IHC-Fr: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Short Description
Iba1 antibody detects Iba1, a protein widely used by neuroscientists as a microglial marker and to gauge microglial activation. It is also expressed in macrophages. Discrimination between these two cell populations can be achieved via double staining with TMEM119 antibody (GTX134087), another useful microglia-specific marker, by identifying brain-residing microglia as Iba1+/TMEM119+ while CNS-infiltrating macrophages are Iba1+/TMEM119-.
GTX635363 Datasheet
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