ATR (phospho Thr1989) antibody [HL132]

Catalogue Number: GTX635571-GTX

Manufacturer:GeneTex
Preservative:No Preservative
Physical state:Liquid
Type:Recombinant Monoclonal
Alias:ATR serine/threonine kinase , FCTCS , FRP1 , MEC1 , SCKL , SCKL1
Shipping Condition:Blue Ice
Unit(s): 25 ul, 100 ul
Host name: Rabbit
Clone: HL132
Isotype: IgG
Immunogen: Carrier-protein conjugated synthetic peptide surrounding phospho Thr1989 of human ATR. The exact sequence is proprietary.
Application: ICC, IF, IHC-P, WB

Description

Description: The protein encoded by this gene is a serine/threonine kinase and DNA damage sensor, activating cell cycle checkpoint signaling upon DNA stress. The encoded protein can phosphorylate and activate several proteins involved in the inhibition of DNA replication and mitosis, and can promote DNA repair, recombination, and apoptosis. This protein is also important for fragile site stability and centrosome duplication. Defects in this gene are a cause of Seckel syndrome 1. [provided by RefSeq, Aug 2017]

Additional Text

Concentration

2 mg/ml

Gene ID

545

Uniprot ID

Q13535

Molecular Weight

301

Purification

Protein A purified

Gene Name

ATR

Antibody Clonality

Recombinant Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Modification

Phosphorylated, Thr1989

Application Notes

WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.