ATR (phospho Thr1989) antibody [HL132]
Catalogue Number: GTX635571-GTX
| Manufacturer: | GeneTex |
| Preservative: | No Preservative |
| Physical state: | Liquid |
| Type: | Recombinant Monoclonal |
| Alias: | ATR serine/threonine kinase , FCTCS , FRP1 , MEC1 , SCKL , SCKL1 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 25 ul, 100 ul |
| Host name: | Rabbit |
| Clone: | HL132 |
| Isotype: | IgG |
| Immunogen: | Carrier-protein conjugated synthetic peptide surrounding phospho Thr1989 of human ATR. The exact sequence is proprietary. |
| Application: | ICC, IF, IHC-P, WB |
Description
Description: The protein encoded by this gene is a serine/threonine kinase and DNA damage sensor, activating cell cycle checkpoint signaling upon DNA stress. The encoded protein can phosphorylate and activate several proteins involved in the inhibition of DNA replication and mitosis, and can promote DNA repair, recombination, and apoptosis. This protein is also important for fragile site stability and centrosome duplication. Defects in this gene are a cause of Seckel syndrome 1. [provided by RefSeq, Aug 2017]
Additional Text
Concentration
2 mg/ml
Gene ID
545
Uniprot ID
Q13535
Molecular Weight
301
Purification
Protein A purified
Gene Name
ATR
Antibody Clonality
Recombinant Monoclonal
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Modification
Phosphorylated, Thr1989
Application Notes
WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
GTX635571 Datasheet
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