Anterior Gradient 2 antibody [HL1024]

Catalogue Number: GTX635838-GTX

Manufacturer:GeneTex
Preservative:No Preservative
Physical state:Liquid
Type:Recombinant Monoclonal
Alias:anterior gradient 2, protein disulphide isomerase family member , AG-2 , AG2 , GOB-4 , HAG-2 , HEL-S-116 , HPC8 , PDIA17 , XAG-2
Shipping Condition:Blue Ice
Unit(s): 100 ul, 25 ul
Host name: Rabbit
Clone: HL1024
Isotype: IgG
Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human Anterior Gradient 2. The exact sequence is proprietary.
Application: ICC, IF, IHC-P, WB

Description

Description: This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, and a C-terminal ER-retention sequence. This protein plays a role in cell migration, cellular transformation and metastasis and is as a p53 inhibitor. As an ER-localized molecular chaperone, it plays a role in the folding, trafficking, and assembly of cysteine-rich transmembrane receptors and the cysteine-rich intestinal gylcoprotein mucin. This gene has been implicated in inflammatory bowel disease and cancer progression. [provided by RefSeq, Mar 2017]

Additional Text

Concentration

1 mg/ml

Gene Name

AGR2

Molecular Weight

20

Uniprot ID

O95994

Gene ID

10551

Purification

Protein A purified

Antibody Clonality

Recombinant Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.