Catalogue Number: GTX636462-GTX
Manufacturer: | GeneTex |
Preservative: | No Preservative |
Physical state: | Liquid |
Type: | Recombinant Monoclonal |
Alias: | insulin , IDDM , IDDM1 , IDDM2 , ILPR , IRDN , MODY10 |
Shipping Condition: | Blue Ice |
Unit(s): | 100 ul, 25 ul |
Host name: | Rabbit |
Clone: | HL1158 |
Isotype: | IgG |
Immunogen: | Synthetic peptide corresponding to human c-peptide. |
Application: | ELISA, IHC-P |
Description: After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]
INS
1 mg/ml
3630
P01308
Protein A purified
Recombinant Monoclonal
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
12
IHC-P: 1:100-1:10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.