C-Peptide antibody [HL1158]

Catalogue Number: GTX636462-GTX

Manufacturer:GeneTex
Preservative:No Preservative
Physical state:Liquid
Type:Recombinant Monoclonal
Alias:insulin , IDDM , IDDM1 , IDDM2 , ILPR , IRDN , MODY10
Shipping Condition:Blue Ice
Unit(s): 100 ul, 25 ul
Host name: Rabbit
Clone: HL1158
Isotype: IgG
Immunogen: Synthetic peptide corresponding to human c-peptide.
Application: ELISA, IHC-P

Description

Description: After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]

Additional Text

Gene Name

INS

Concentration

1 mg/ml

Gene ID

3630

Uniprot ID

P01308

Purification

Protein A purified

Antibody Clonality

Recombinant Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Molecular Weight

12

Application Notes

IHC-P: 1:100-1:10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.