Artemis antibody [HL1227]
Catalogue Number: GTX636575-GTX
| Manufacturer: | GeneTex |
| Preservative: | No Preservative |
| Physical state: | Liquid |
| Type: | Recombinant Monoclonal |
| Alias: | DNA cross-link repair 1C , A-SCID , DCLREC1C , RS-SCID , SCIDA , SNM1C |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul, 25 ul |
| Host name: | Rabbit |
| Clone: | HL1227 |
| Isotype: | IgG |
| Immunogen: | Recombinant protein encompassing a sequence within the center region of human Artemis. The exact sequence is proprietary. |
| Application: | ICC, IF, WB |
Description
Description: This gene encodes a nuclear protein that is involved in V(D)J recombination and DNA repair. The encoded protein has single-strand-specific 5'-3' exonuclease activity; it also exhibits endonuclease activity on 5' and 3' overhangs and hairpins. The protein also functions in the regulation of the cell cycle in response to DNA damage. Mutations in this gene can cause Athabascan-type severe combined immunodeficiency (SCIDA) and Omenn syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
Additional Text
Concentration
1 mg/ml
Gene Name
DCLRE1C
Gene ID
64421
Uniprot ID
Q96SD1
Molecular Weight
78
Purification
Protein A purified
Antibody Clonality
Recombinant Monoclonal
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Application Notes
WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
GTX636575 Datasheet
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