MMP1 antibody [HL1259]

Catalogue Number: GTX636661-GTX

Manufacturer:GeneTex
Preservative:no preservative|No Preservative
Molecular Weight:54
Physical state:Liquid
Type:Recombinant Monoclonal
Alias:matrix metallopeptidase 1 , CLG , CLGN
Shipping Condition:Blue Ice
Unit(s): 100 ul, 25 ul
Host name: Rabbit
Clone: HL1259
Isotype: IgG
Immunogen: Recombinant protein encompassing a sequence within the center region of Human MMP1. The exact sequence is proprietary.
Application: ICC, IF, IHC-P, WB

Description

Description: This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease breaks down the interstitial collagens, including types I, II, and III. The gene is part of a cluster of MMP genes on chromosome 11. Mutations in this gene are associated with chronic obstructive pulmonary disease (COPD). Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016]

Additional Text

Gene ID

4312

Gene Name

MMP1

Uniprot ID

P03956

Purification

Protein A purified

Antibody Clonality

Recombinant Monoclonal

Concentration

1 mg/ml

Application Notes

IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.