Mre11 antibody [HL1385]
Catalogue Number: GTX636825-GTX
GTX636825 Image
GTX636825 Image
GTX636825 Image
GTX636825 Image
GTX636825 Image
GTX636825 Image
Various whole cell extracts (30 µg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with Mre11 antibody [HL1385] (GTX636825) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
GTX636825 Image
Various whole cell extracts (30 µg) were separated by 7.5% SDS-PAGE, and the membranes were blotted with Mre11 antibody [HL1385] (GTX636825) diluted at 1:1000 and competitor's antibody (# Highly Cited Antibody) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody. *The competitor is not affiliated with GeneTex and does not endorse this product.
GTX636825 Image
Whole cell extract (30 µg) was separated by 7.5% SDS-PAGE, and the membrane was blotted with Mre11 antibody [HL1385] (GTX636825) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
GTX636825 Image
Mre11 antibody [HL1385] detects Mre11 protein at nucleus by immunohistochemical analysis. Sample: Paraffin-embedded human colon cancer. Mre11 stained by Mre11 antibody [HL1385] (GTX636825) diluted at 1:100. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min
GTX636825 Image
Non-transfected (-) and transfected (+) HeLa whole cell extracts (30 µg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with Mre11 antibody [HL1385] (GTX636825) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
| Manufacturer: | GeneTex |
| Preservative: | no preservative|No Preservative |
| Molecular Weight: | 81 |
| Physical state: | Liquid |
| Type: | Recombinant Monoclonal |
| Alias: | MRE11 homolog, double strand break repair nuclease , ATLD , HNGS1 , MRE11A , MRE11B |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul, 25 ul |
| Host name: | Rabbit |
| Clone: | HL1385 |
| Isotype: | IgG |
| Immunogen: | Recombinant protein encompassing a sequence within the center region of human Mre11. The exact sequence is proprietary. |
| Application: | IHC-P, WB |
Description
Description: This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Additional Text
Gene ID
4361
Uniprot ID
P49959
Gene Name
MRE11
Purification
Protein A purified
Antibody Clonality
Recombinant Monoclonal
Concentration
1 mg/ml
Application Notes
WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Storage Note
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
GTX636825 Datasheet
SUPPORT
outstanding technical support
PRODUCT
we offer a full product guarantee
DELIVERY
we offer free delivery to UK universities and non profit organisations