SOD1 antibody [HL1652]

Catalogue Number: GTX637250-GTX

Manufacturer:GeneTex
Preservative:no preservative|No Preservative
Molecular Weight:16
Physical state:Liquid
Type:Recombinant Monoclonal
Alias:superoxide dismutase 1 , ALS , ALS1 , HEL-S-44 , IPOA , SOD , hSod1 , homodimer
Shipping Condition:Blue Ice
Unit(s): 100 ul, 25 ul
Host name: Rabbit
Clone: HL1652
Isotype: IgG
Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human SOD1. The exact sequence is proprietary.
Application: IHC-P, WB

Description

Description: The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene. [provided by RefSeq, Jul 2008]

Additional Text

Gene Name

SOD1

Gene ID

6647

Uniprot ID

P00441

Purification

Protein A purified

Antibody Clonality

Recombinant Monoclonal

Concentration

1 mg/ml

Application Notes

IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.