EPO antibody [HL1793]

Catalogue Number: GTX637445-GTX

Manufacturer:GeneTex
Preservative:no preservative|No Preservative
Molecular Weight:21
Physical state:Liquid
Type:Recombinant Monoclonal
Alias:erythropoietin , DBAL , ECYT5 , EP , MVCD2
Shipping Condition:Blue Ice
Unit(s): 100 ul, 25 ul
Host name: Rabbit
Clone: HL1793
Isotype: IgG
Immunogen: Recombinant fragment of human EPO
Application: ELISA, sELISA, WB

Description

Description: This gene encodes a secreted, glycosylated cytokine composed of four alpha helical bundles. The encoded protein is mainly synthesized in the kidney, secreted into the blood plasma, and binds to the erythropoietin receptor to promote red blood cell production, or erythropoiesis, in the bone marrow. Expression of this gene is upregulated under hypoxic conditions, in turn leading to increased erythropoiesis and enhanced oxygen-carrying capacity of the blood. Expression of this gene has also been observed in brain and in the eye, and elevated expression levels have been observed in diabetic retinopathy and ocular hypertension. Recombinant forms of the encoded protein exhibit neuroprotective activity against a variety of potential brain injuries, as well as antiapoptotic functions in several tissue types, and have been used in the treatment of anemia and to enhance the efficacy of cancer therapies. [provided by RefSeq, Aug 2017]

Additional Text

Gene Name

EPO

Gene ID

2056

Uniprot ID

P01588

Purification

Protein A purified

Antibody Clonality

Recombinant Monoclonal

Molecular Weight

21

Concentration

1 mg/ml

Application Notes

*Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.