S100 beta antibody [HL2228]

Catalogue Number: GTX638273-GTX

Preservative:No Preservative
Physical state:Liquid
Type:Recombinant Monoclonal
Alias:S100 calcium binding protein B , NEF , S100 , S100-B , S100beta
Shipping Condition:Blue Ice
Unit(s): 100 ul, 25 ul
Host name: Rabbit
Clone: HL2228
Isotype: IgG
Immunogen: Full length human S100 beta recombinant protein
Application: IHC-P, WB


Description: The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes. [provided by RefSeq, Jul 2008]

Additional Text

Gene Name



1 mg/ml

Gene ID


Uniprot ID



Protein A purified

Antibody Clonality

Recombinant Monoclonal

Application Notes

WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.