SDHB antibody [HL2251]
Catalogue Number: GTX638300-GTX
GTX638300 Image
GTX638300 Image
GTX638300 Image
GTX638300 Image
GTX638300 Image
Various whole cell extracts (30 µg) were separated by 12% SDS-PAGE, and the membrane was blotted with SDHB antibody [HL2251] (GTX638300) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
GTX638300 Image
SDHB antibody [HL2251] detects SDHB protein at mitochondria by immunohistochemical analysis. Sample: Paraffin-embedded dog brain. SDHB stained by SDHB antibody [HL2251] (GTX638300) diluted at 1:100. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min
GTX638300 Image
SDHB antibody [HL2251] detects SDHB protein by immunohistochemical analysis. Sample: Paraffin-embedded human kidney. SDHB stained by SDHB antibody [HL2251] (GTX638300) diluted at 1:200. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min
GTX638300 Image
SDHB antibody [HL2251] detects SDHB protein by immunohistochemical analysis. Sample: Paraffin-embedded human tissues. SDHB stained by SDHB antibody [HL2251] (GTX638300) diluted at 1:200. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min
| Manufacturer: | GeneTex |
| Preservative: | no preservative|No preservative |
| Molecular Weight: | 32 |
| Physical state: | Liquid |
| Type: | Recombinant Monoclonal |
| Alias: | succinate dehydrogenase complex iron sulfur subunit B , CWS2 , IP , PGL4 , SDH , SDH1 , SDH2 , SDHIP |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul, 25 ul |
| Host name: | Rabbit |
| Clone: | HL2251 |
| Isotype: | IgG |
| Immunogen: | Recombinant fragment of human SDHB. |
| Application: | IHC-P, WB |
Description
Description: Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis. [provided by RefSeq, Jul 2008]
Additional Text
Gene Name
SDHB
Uniprot ID
P21912
Gene ID
6390
Purification
Protein A purified
Antibody Clonality
Recombinant Monoclonal
Concentration
1 mg/ml
Application Notes
WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Storage Note
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
GTX638300 Datasheet
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