GLP1R antibody [HL2297]

Catalogue Number: GTX638352-GTX

Manufacturer:GeneTex
Preservative:no preservative|No preservative
Physical state:Liquid
Type:Recombinant Monoclonal
Alias:glucagon like peptide 1 receptor , GLP-1 , GLP-1-R , GLP-1R
Shipping Condition:Blue Ice
Unit(s): 100 ul, 25 ul
Host name: Rabbit
Clone: HL2297
Isotype: IgG
Immunogen: Synthetic peptide encompassing a sequence within the Extracellular domain human of GLP1R. The exact sequence is proprietary.
Application: IHC-P

Description

Description: This gene encodes a 7-transmembrane protein that functions as a receptor for glucagon-like peptide 1 (GLP-1) hormone, which stimulates glucose-induced insulin secretion. This receptor, which functions at the cell surface, becomes internalized in response to GLP-1 and GLP-1 analogs, and it plays an important role in the signaling cascades leading to insulin secretion. It also displays neuroprotective effects in animal models. Polymorphisms in this gene are associated with diabetes. The protein is an important drug target for the treatment of type 2 diabetes and stroke. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2016]

Additional Text

Gene ID

2740

Concentration

2 mg/ml

Gene Name

GLP1R

Uniprot ID

P43220

Purification

Protein A purified

Antibody Clonality

Recombinant Monoclonal

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.