IGF2R antibody [GT1078]
Catalogue Number: GTX64270-GTX
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FACS analysis of HeLa cells using GTX64270 IGF2 Receptor antibody [GT1078]. Blue : Primary antibody Red : Isotype control
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ICC/IF analysis of HepG2 cells using GTX64270 IGF2 Receptor antibody [GT1078]. Fixation : 4% PFA Permeabilization : 0.25% Triton X-100 in PBS Green : Primary antibody Blue : DAPI
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ICC/IF analysis of MCF-7 cells using GTX64270 IGF2 Receptor antibody [GT1078]. Fixation : 4% PFA Permeabilization : 0.25% Triton X-100 in PBS Green : Primary antibody Blue : DAPI
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ICC/IF analysis of HeLa cells using GTX64270 IGF2 Receptor antibody [GT1078]. Fixation : 4% PFA Permeabilization : 0.25% Triton X-100 in PBS Green : Primary antibody Blue : DAPI
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IHC-P analysis of human tonsil tissue using GTX64270 IGF2 Receptor antibody [GT1078].
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Various whole cell extracts (30 µg) were separated by 5% SDS-PAGE, and the membrane was blotted with IGF2R antibody [GT1078] (GTX64270) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody. Corresponding RNA expression data for the same cell lines are based on Human Protein Atlas program.
| Manufacturer: | GeneTex |
| Preservative: | 0.05% Sodium azide|0.05% Sodium azide |
| Molecular Weight: | 274 |
| Physical state: | Liquid |
| Type: | Recombinant Monoclonal |
| Alias: | Insulin Like Growth Factor 2 Receptor , Cd222 , Ci-M6Pr , Cimpr , M6P-R , M6P/Igf2R , Mpr 300 , Mpr1 , Mpr300 , Mpri , Igf2R |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Rabbit |
| Clone: | GT1078 |
| Isotype: | IgG |
| Immunogen: | |
| Application: | FC, ICC, IF, IHC-P, WB |
Description
Description: This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate, although the binding sites for either are located on different segments of the receptor. This receptor functions in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. While the related mouse gene shows exclusive expression from the maternal allele, imprinting of the human gene appears to be polymorphic, with only a minority of individuals showing expression from the maternal allele. [provided by RefSeq, Apr 2013]
Additional Text
Gene Name
IGF2R
Gene ID
3482
Molecular Weight
274
Purification
Protein A purified
Antibody Clonality
Recombinant Monoclonal
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Storage Note
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Application Notes
WB: 1:1000-5000. ICC/IF: 1:50-1:200. IHC-P: 1:50-1:200. FCM: 1:50-1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
GTX64270 Datasheet
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