Caldesmon antibody [GT1108]

Catalogue Number: GTX64300-GTX

Manufacturer:GeneTex
Preservative:0.05% Sodium azide|0.05% Sodium azide
Molecular Weight:93
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Alias:Caldesmon 1 , Cdm , H-Cad , Hcad , L-Cad , Lcad , Nag22 , Cald1
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Rabbit
Clone: GT1108
Isotype: IgG
Immunogen:
Application: FC, ICC, IF, IHC-P, WB

Description

Description: This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]

Additional Text

Gene Name

CALD1

Gene ID

800

Molecular Weight

93

Purification

Protein A purified

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Application Notes

WB: 1:1000-2000. ICC/IF: 1:50-1:200. IHC-P: 1:50-1:200. FCM: 1:50-1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.