Human Jagged 1 protein, human IgG1 Fc tag (active)
Catalogue Number: GTX65636-PRO-GTX
GTX65636-PRO Image
GTX65636-PRO Image
GTX65636-PRO Image
Adipogenesis inhibition of 3T3L-1 cells. When the cells were confluently grown adipogenesis was initiated by adding IBMX, Dexamethasone, and insulin to 0.5mM, 1µM, and 10µg/ml, respectively and continued for 2 days (day 0).The medium was replaced every 2 days with new medium containing insulin in the presence or absence of 5µg/ml of human Jagged1-Fc (GTX65636-pro) and human CD137-Fc as a control-Fc. Staining with Oil Red O was typically performed on day 7.
GTX65636-PRO Image
Induction of Hes-1 with the treatment of GTX65636-pro Jagged 1 Fc fusion protein. A mouse preadpipocyte cell line, 3T3L1, was stimulated with 5µg/ml of human Jagged1-Fc fusion protein as in indicated time points and each cell lysate was prepared and subjected to western blot by using human Hes1 antibody or GAPDH antibody.
| Manufacturer: | GeneTex |
| Preservative: | no preservative|No preservative |
| Physical state: | Liquid |
| Type: | Bioactive Proteins |
| Alias: | jagged canonical Notch ligand 1 , AGS , AGS1 , AHD , AWS , CD339 , DCHE , HJ1 , JAGL1 |
| Host Cell: | HEK293 cells |
| Shipping Condition: | Dry Ice |
| Unit(s): | 10 ug |
| Application: | FA |
Additional Text
Gene ID
182
Gene Name
JAG1
Concentration
0.5 mg/ml
Protein Tag
hIgG1 Fc Tag
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Application Notes
Inhibits adipogenesis of mesenchymal stem cells (MSCs). Induces Hes-1 in 3T3L-1 cells.
Storage Note
Store as concentrated solution. Aliquot and store at -20C or below. Avoid freeze-thaw cycles.
GTX65636-PRO Datasheet
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