Human B7-H4 protein, human IgG1 Fc tag (active)

Catalogue Number: GTX65697-PRO-GTX

Manufacturer:GeneTex
Preservative:no preservative|No preservative
Physical state:Lyophilized
Type:Immune Checkpoint Proteins
Alias:V-set domain containing T cell activation inhibitor 1 , B7-H4 , B7H4 , B7S1 , B7X , B7h.5 , PRO1291 , VCTN1
Host Cell:CHO Cells
Shipping Condition:Blue Ice
Unit(s): 100 ug
Application: FA

Additional Text

Gene Name

VTCN1

Gene ID

79679

Protein Tag

hIgG1 Fc Tag

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Application Notes

Measured by the ablility to inhibit anti-CD3-induced proliferation of stimulated human T cells. Human T lymphocytes cultured for 72 hours with PHA were incubated for an additional 3 days in 96 well place coated with 500ng/ml anti-CD3 and 10 µg/ml human B7H4/Fc. The presence of human B7H4/Fc at 10 µg/ml inhibited anti CD3 response by 30-50%. Optimal dilutions should be determined by each laboratory for each application.

Storage Note

Store at -20C or below. After reconstitution, keep as concentrated solution. Aliquot and avoid freeze-thaw cycles.