Human CTLA4 protein, mutant human IgG1 Fc tag (active)
Catalogue Number: GTX65744-PRO-GTX
| Manufacturer: | GeneTex |
| Preservative: | no preservative|No preservative |
| Physical state: | Lyophilized |
| Type: | Immune Checkpoint Proteins |
| Alias: | cytotoxic T-lymphocyte associated protein 4 , ALPS5 , CD , CD152 , CELIAC3 , CTLA-4 , GRD4 , GSE , IDDM12 |
| Host Cell: | CHO Cells |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
| Application: | FA |
Additional Text
Gene ID
1493
Gene Name
CTLA4
Protein Tag
hMutIgG1 Fc Tag
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Application Notes
Measured by its ability to inhibit IL-2 secretion by stimulated Jurkat human acute T cell leukemia cells.
Short Description
Non-lytic: Acts as a long lasting fusion protein which only binds to the receptor. Mutations to the complement (C1q) and FcgR I binding sites of the IgGs Fc fragment render the fusion proteins incapable of antibody directed cytotoxicity (ADCC) and complement directed cytotoxicity (CDC).
Storage Note
Store at -20C or below. After reconstitution, keep as concentrated solution. Aliquot and avoid freeze-thaw cycles.
GTX65744-PRO Datasheet
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