Human ICOS Ligand protein, mutant human IgG1 Fc tag (active)

Catalogue Number: GTX65746-PRO-GTX

Manufacturer:	GeneTex
Preservative:	no preservative\|No preservative
Physical state:	Lyophilized
Type:	Protein Ligand
Alias:	inducible T cell costimulator ligand , B7-H2 , B7H2 , B7RP-1 , B7RP1 , CD275 , GL50 , ICOS-L , ICOSL , LICOS
Host Cell:	CHO Cells
Shipping Condition:	Blue Ice
Unit(s):	100 ug
Application:	FA

Overview
Datasheets

Additional Text

Gene Name

ICOSLG

Gene ID

23308

Protein Tag

hMutIgG1 Fc Tag

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Application Notes

Measured by its ability to stimulate human T cell proliferation in the presence of anti-CD3.

Short Description

Non-lytic: Acts as a long lasting fusion protein which only binds to the receptor. Mutations to the complement (C1q) and FcgR I binding sites of the IgGs Fc fragment render the fusion proteins incapable of antibody directed cytotoxicity (ADCC) and complement directed cytotoxicity (CDC).

Storage Note

Store at -20C or below. After reconstitution, keep as concentrated solution. Aliquot and avoid freeze-thaw cycles.

GTX65746-PRO Datasheet

Price

£444.00

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