Mouse Cystatin C protein, His tag (active)

Catalogue Number: GTX66963-PRO-GTX

Manufacturer:GeneTex
Preservative:no preservative|No preservative
Physical state:Liquid
Type:Protease Inhibitor Protein
Alias:cystatin C , CysC
Host Cell:Baculovirus
Shipping Condition:Dry Ice
Unit(s): 10 ug
Application: FA

Description

Description: The protein encoded by this gene is a cysteine protease inhibitor involved in neurodegenerative and cardiovascular processes. The encoded protein inhibits aggregation of beta-amyloid protein, a hallmark of Alzheimer's disease, so it may be useful as a therapeutic. This protein also may be a biomarker for atherosclerosis. [provided by RefSeq, Aug 2015]

Additional Text

Gene Name

CST3

Uniprot ID

P21460

Gene ID

13010

Protein Tag

HIS Tag

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Concentration

1 mg/ml

Application Notes

The IC₅₀ value is < 1.0 nM. The inhibitory function of Cystatin 3 on protease activity of papain was measured by a fluorometric assay using Z-FR-AMC at pH 7.5 at 25C.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.