Human DcR2 / CD264 protein, human IgG1 Fc and His tag (active)

Catalogue Number: GTX66967-PRO-GTX

Manufacturer:GeneTex
Preservative:no preservative|No preservative
Physical state:Liquid
Type:Bioactive Proteins
Alias:TNF receptor superfamily member 10d , CD264 , DCR2 , TRAIL-R4 , TRAILR4 , TRUNDD
Host Cell:Baculovirus
Shipping Condition:Dry Ice
Unit(s): 10 ug
Application: FA

Description

Description: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain, a transmembrane domain, and a truncated cytoplamic death domain. This receptor does not induce apoptosis, and has been shown to play an inhibitory role in TRAIL-induced cell apoptosis. [provided by RefSeq, Jul 2008]

Additional Text

Gene Name

TNFRSF10D

Gene ID

8793

Uniprot ID

Q9UBN6

Concentration

0.5 mg/ml

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Application Notes

Measured in a neutralizing assay using Jurkat human T lymphocyte. The ED₅₀ for this effect is less or equal to 10 ng/ml in the presence of 2 ng/ml TRAIL.

Protein Tag

hIgG Fc-HIS Tag, hIgG1 Fc Tag, HIS Tag

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.