Human IL1 Receptor 2 protein, His tag (active)

Catalogue Number: GTX67059-PRO-GTX

Manufacturer:	GeneTex
Preservative:	no preservative\|No preservative
Physical state:	Liquid
Type:	Bioactive Proteins
Alias:	interleukin 1 receptor type 2 , CD121b , CDw121b , IL-1R-2 , IL-1RT-2 , IL-1RT2 , IL1R2c , IL1RB
Host Cell:	Baculovirus
Shipping Condition:	Dry Ice
Unit(s):	10 ug
Application:	FA

Overview
Datasheets

Description

Description: The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Alternative splicing results in multiple transcript variants and protein isoforms. Alternative splicing produces both membrane-bound and soluble proteins. A soluble protein is also produced by proteolytic cleavage. [provided by RefSeq, May 2012]

Additional Text

Gene ID

7850

Gene Name

IL1R2

Uniprot ID

P27930

Concentration

0.5 mg/ml

Protein Tag

HIS Tag

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Application Notes

Measured by its ability to inhibit proliferation using D10.G4.1 mouse helper T cells. The ED₅₀ for this effect is less or equal to 400 ng/ml with IL-1 beta.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

GTX67059-PRO Datasheet

Price

£192.00

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Quantity
Unit Size

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