Mouse IL6 protein, His tag (active)

Catalogue Number: GTX67072-PRO-GTX

Manufacturer:GeneTex
Preservative:no preservative|No preservative
Physical state:Liquid
Type:Interleukins
Alias:interleukin 6 , IL-6
Host Cell:Baculovirus
Shipping Condition:Dry Ice
Unit(s): 50 ug
Application: FA

Description

Description: This gene encodes a member of the interleukin family of cytokines that have important functions in immune response, hematopoiesis, inflammation and the acute phase response. The ectopic overexpression of the encoded protein in mice results in excessive plasma cells in circulation, leading to death. Mice lacking the encoded protein exhibit abnormalities in hepatic acute phase response, some immune mechanisms, bone resorption in response to estrogen, liver regeneration and wound healing. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2015]

Additional Text

Gene Name

IL6

Gene ID

16193

Concentration

0.5 mg/ml

Uniprot ID

P08505

Protein Tag

HIS Tag

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Application Notes

Measured in a cell proliferation assay using M-NFS-60 mouse B cells. The ED₅₀ for this effects is less or equal to 0.1 ng/ml.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.