Human VCAM1 / CD106 protein, His tag (active)

Catalogue Number: GTX67183-PRO-GTX

Manufacturer:GeneTex
Preservative:no preservative|No preservative
Physical state:Liquid
Type:Bioactive Proteins
Alias:vascular cell adhesion molecule 1 , CD106 , INCAM-100
Host Cell:Baculovirus
Shipping Condition:Dry Ice
Unit(s): 50 ug
Application: FA

Description

Description: This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Three alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq, Dec 2010]

Additional Text

Gene Name

VCAM1

Gene ID

7412

Concentration

0.5 mg/ml

Uniprot ID

P19320

Protein Tag

HIS Tag

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Application Notes

Measured by the ability of the immobilized protein to support the adhesion of U937 Human histiocytic lymphoma cells. When cells are added to VCAM1 coated plates 10 µg/ml. This effect is more to 70%.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.