Human JNK3 protein, His tag

Catalogue Number: GTX67680-PRO-GTX

Manufacturer:GeneTex
Preservative:no preservative|No preservative
Physical state:Liquid
Type:Protein Kinases
Alias:mitogen-activated protein kinase 10 , JNK3 , JNK3A , PRKM10 , SAPK1b , p493F12 , p54bSAPK
Host Cell:Baculovirus
Shipping Condition:Dry Ice
Unit(s): 10 ug

Description

Description: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as integration points for multiple biochemical signals, and thus are involved in a wide variety of cellular processes, such as proliferation, differentiation, transcription regulation and development. This kinase is specifically expressed in a subset of neurons in the nervous system, and is activated by threonine and tyrosine phosphorylation. Targeted deletion of this gene in mice suggests that it may have a role in stress-induced neuronal apoptosis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. A recent study provided evidence for translational readthrough in this gene, and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon. [provided by RefSeq, Dec 2017]

Additional Text

Gene Name

MAPK10

Gene ID

5602

Concentration

0.25 mg/ml

Uniprot ID

P53779

Protein Tag

HIS Tag

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.