Human TDP1 protein, His tag
Catalogue Number: GTX68612-PRO-GTX
| Manufacturer: | GeneTex |
| Preservative: | no preservative|No preservative |
| Physical state: | Liquid |
| Type: | Other Proteins |
| Alias: | tyrosyl-DNA phosphodiesterase 1 |
| Host Cell: | Baculovirus |
| Shipping Condition: | Dry Ice |
| Unit(s): | 10 ug |
Description
Description: The protein encoded by this gene is involved in repairing stalled topoisomerase I-DNA complexes by catalyzing the hydrolysis of the phosphodiester bond between the tyrosine residue of topoisomerase I and the 3-prime phosphate of DNA. This protein may also remove glycolate from single-stranded DNA containing 3-prime phosphoglycolate, suggesting a role in repair of free-radical mediated DNA double-strand breaks. This gene is a member of the phospholipase D family and contains two PLD phosphodiesterase domains. Mutations in this gene are associated with the disease spinocerebellar ataxia with axonal neuropathy (SCAN1). [provided by RefSeq, Aug 2016]
Additional Text
Gene Name
TDP1
Uniprot ID
Q9NUW8
Concentration
0.25 mg/ml
Gene ID
55775
Protein Tag
HIS Tag
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Storage Note
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
GTX68612-PRO Datasheet
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