Hec1 (phospho Ser 76/77) antibody

Catalogue Number: GTX70015-GTX

Manufacturer:GeneTex
Preservative:No Preservative
Physical state:Liquid
Type:Polyclonal Primary Antibody - Unconjugated
Alias:NDC80 kinetochore complex component , HEC , HEC1 , HsHec1 , KNTC2 , TID3 , hsNDC80
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Hec1 (phospho Ser 76/77). The exact sequence is proprietary.
Application: ELISA, ICC, IF, WB

Description

Description: This gene encodes a component of the NDC80 kinetochore complex. The encoded protein consists of an N-terminal microtubule binding domain and a C-terminal coiled-coiled domain that interacts with other components of the complex. This protein functions to organize and stabilize microtubule-kinetochore interactions and is required for proper chromosome segregation. [provided by RefSeq, Oct 2011]

Additional Text

Gene ID

10403

Gene Name

NDC80

Uniprot ID

O14777

Purification

Affinity Purified

Molecular Weight

74

Concentration

0.079 mg/ml

Antibody Clonality

Polyclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Modification

Phosphorylated, Ser76

Application Notes

Recommended Starting Dilutions:For WB: Use at a dilution of 1:300For ICC/IF: Use at a dilution of 1:150Not yet tested in other applications. Optimal dilutions should be determined experimentally by the researcher.