Estrogen Receptor alpha antibody [1F3]

Catalogue Number: GTX70171-GTX

Manufacturer:GeneTex
Preservative:No Preservative
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Alias:estrogen receptor 1 , ER , ESR , ESRA , ESTRR , Era , NR3A1
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Mouse
Clone: 1F3
Isotype: IgG1
Immunogen: The region encoding amino acids 1-190 expressed in E. coli.
Application: FACS, IP, WB, IHC-Fr

Description

Description: This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined. [provided by RefSeq, Mar 2014]

Additional Text

Gene ID

2099

Gene Name

ESR1

Molecular Weight

66

Uniprot ID

P03372

Purification

Protein G purified

Concentration

1.56 mg/ml

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

WB: 1:500-1:3000. IP: 1 - 5 µg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.