Estrogen Receptor beta antibody [14C8]
Catalogue Number: GTX70174-GTX
| Manufacturer: | GeneTex |
| Preservative: | No Preservative |
| Physical state: | Liquid |
| Type: | ChIP Validated Antibodies |
| Alias: | estrogen receptor 2 , ER-BETA , ESR-BETA , ESRB , ESTRB , Erb , NR3A2 , ODG8 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Mouse |
| Clone: | 14C8 |
| Isotype: | IgG2b |
| Immunogen: | Amino acids 1-153 of human ER-beta expressed in E. coli. |
| Application: | FACS, ICC, IF, IHC-P, ChIP, WB, IHC-Fr, DB, IHC |
Description
Description: This gene encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized. [provided by RefSeq, Jul 2008]
Additional Text
Gene Name
ESR2
Gene ID
2100
Molecular Weight
59
Uniprot ID
Q92731
Purification
Protein G purified
Concentration
1.23 mg/ml
Antibody Clonality
Monoclonal
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Application Notes
For IHC, a recommended protocol is provided. For WB: Use at a concentration of 1-5 µg/ml. For ChIP: Use at an dependent assay. Optimal dilutions/concentrations should be determined by the researcher.
GTX70174 Datasheet
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