NBS1 antibody [1C3]

Catalogue Number: GTX70222-GTX

Manufacturer:GeneTex
Preservative:No Preservative
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Alias:nibrin , AT-V1 , AT-V2 , ATV , NBS , NBS1 , P95
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Mouse
Clone: 1C3
Isotype: IgG1
Immunogen: The complete coding region of the human p95/NBS1 expressed in E. coli.
Application: ICC, IF, IP, WB

Description

Description: Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. [provided by RefSeq, Jul 2008]

Additional Text

Concentration

1 mg/ml

Gene ID

4683

Gene Name

NBN

Uniprot ID

O60934

Purification

Protein G purified

Molecular Weight

85

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

WB: 1:500-1:3000. ICC/IF: 1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.