CtIP antibody [19E8]
Catalogue Number: GTX70264-GTX
| Manufacturer: | GeneTex |
| Preservative: | No preservative |
| Physical state: | Liquid |
| Type: | ChIP Validated Antibodies |
| Alias: | RB binding protein 8, endonuclease , COM1 , CTIP , JWDS , RIM , SAE2 , SCKL2 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Mouse |
| Clone: | |
| Isotype: | IgG1 |
| Immunogen: | Human CtIP |
| Application: | ICC, IF, IP, ChIP, WB, PLA |
Description
Description: The protein encoded by this gene is a ubiquitously expressed nuclear protein. It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. This protein complexes with transcriptional co-repressor CTBP. It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation, DNA repair, and/or cell cycle checkpoint control. It is suggested that this gene may itself be a tumor suppressor acting in the same pathway as BRCA1. Three transcript variants encoding two different isoforms have been found for this gene. More transcript variants exist, but their full-length natures have not been determined. [provided by RefSeq, Jul 2008]
Additional Text
Concentration
1 mg/ml
Gene Name
RBBP8
Molecular Weight
102
Gene ID
5932
Uniprot ID
Q99708
Purification
Protein G purified
Antibody Clonality
Monoclonal
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Application Notes
WB: 1:500-1:1000. ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
GTX70264 Datasheet
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