FANCD2 antibody [103]

Catalogue Number: GTX70299-GTX

Manufacturer:	GeneTex
Preservative:	No Preservative
Physical state:	Liquid
Type:	Monoclonal Primary Antibody - Unconjugated
Alias:	FA complementation group D2 , FA-D2 , FA4 , FACD , FAD , FAD2 , FANCD
Shipping Condition:	Blue Ice
Unit(s):	100 ul
Host name:	Mouse
Clone:	103
Isotype:	IgG1
Immunogen:	Human FANCD2 fusion protein
Application:	ELISA, ICC, IF, WB

Overview
Datasheets

Description

Description: The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group D2. This protein is monoubiquinated in response to DNA damage, resulting in its localization to nuclear foci with other proteins (BRCA1 AND BRCA2) involved in homology-directed DNA repair. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]

Additional Text

Concentration

1 mg/ml

Gene ID

2177

Gene Name

FANCD2

Uniprot ID

Q9BXW9

Purification

Protein G purified

Molecular Weight

164

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

GTX70299 Datasheet

Price

£285.00

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