53BP1 antibody
Catalogue Number: GTX70310-GTX
| Manufacturer: | GeneTex |
| Preservative: | No Preservative |
| Physical state: | Liquid |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | tumor protein p53 binding protein 1 , 53BP1 , TDRD30 , p202 , p53BP1 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | Synthetic peptide corresponding to the carboxy-terminus of h53BP1, conjugated to a carrier protein. |
| Application: | ICC, IF, IHC-P, WB, IHC |
Description
Description: P53-binding protein 1 (53BP1) plays a critical role in tumor suppression and is a putative substrate of ATM kinase. Upon DNA damage, it is phosphorylated and relocalizes to the presumptive sites of damage, specifically, double-strand breaks. This also suggests a role in DNA repair, maintaining genomic stability.
Additional Text
Gene Name
TP53BP1
Uniprot ID
Q12888
Gene ID
7158
Concentration
0.83 mg/ml
Purification
Affinity Purified
Molecular Weight
214
Antibody Clonality
Polyclonal
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Application Notes
Suggested starting dilutions are as follows: WB: 1:500-1:3000, ICC/IF: 1:100-1:1000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
GTX70310 Datasheet
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