CD11b antibody [2LPM19c]

Catalogue Number: GTX72023-GTX

Manufacturer:	GeneTex
Preservative:	0.09% sodium azide
Molecular Weight:	127
Physical state:	Liquid
Type:	Monoclonal Primary Antibody - Unconjugated
Alias:	integrin subunit alpha M , CD11B , CR3A , MAC-1 , MAC1A , MO1A , SLEB6
Shipping Condition:	Blue Ice
Unit(s):	500 ul
Host name:	Mouse
Clone:	2LPM19c
Isotype:	IgG1
Immunogen:	Purified C3bi Receptor
Application:	FC, IHC-Fr, NT, Inh, Act

Overview
Datasheets

Description

Description: This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]

Additional Text

Gene Name

ITGAM

Gene ID

3684

Uniprot ID

P11215

Concentration

0.1 mg/ml

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

For a three-step avidin-biotin complex system, a dilution of 1:50 to 1:100 may be used as a guideline. Dilute according to the particular application being used. In general, the 0.05M Borate pH 8.0 containing 0.15M Sodium Chloride, 0.05% Sodium Azide, is a good diluent to use with most antibodies. Optimal dilutions/concentrations should be determined by the researcher.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4C. DO NOT FREEZE.

GTX72023 Datasheet

GTX72023 Reference

Price

£349.00

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