alpha Smooth Muscle Actin antibody [1A4] (FITC)

Catalogue Number: GTX72531-GTX

Manufacturer:GeneTex
Preservative:0.05% Sodium azide|0.05% Sodium azide
Molecular Weight:42
Physical state:Liquid
Type:Monoclonal Primary Antibody - Conjugated
Alias:actin alpha 2, smooth muscle , ACTSA
Shipping Condition:Blue Ice
Unit(s): 100 ug
Host name: Mouse
Clone: 1A4
Isotype: IgG2a
Immunogen: The N-terminal decapeptide of alpha-smooth muscle actin
Application: FC, ICC, IF, IHC-P, IHC-Fr

Description

Description: This gene encodes one of six different actin proteins. Actins are highly conserved proteins that are involved in cell motility, structure, integrity, and intercellular signaling. The encoded protein is a smooth muscle actin that is involved in vascular contractility and blood pressure homeostasis. Mutations in this gene cause a variety of vascular diseases, such as thoracic aortic disease, coronary artery disease, stroke, and Moyamoya disease, as well as multisystemic smooth muscle dysfunction syndrome. [provided by RefSeq, Sep 2017]

Additional Text

Gene Name

ACTA2

Gene ID

59

Uniprot ID

P62736

Purification

Unpurified

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

For IF: Use at 10-20 µg/ml for 2 hours at room temperature. For IF: paraffin-embedded or frozen sections, as well as on cell smears can be used. Optimal dilutions/concentrations should be determined by the end user.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4C. DO NOT FREEZE. Protect from light.