C3 antibody

Catalogue Number: GTX72994-GTX

Manufacturer:GeneTex
Preservative:0.1% Sodium azide
Molecular Weight:187
Physical state:Liquid
Type:Polyclonal Primary Antibody - Unconjugated
Alias:complement C3 , AHUS5 , ARMD9 , ASP , C3a , C3b , CPAMD1 , HEL-S-62p
Shipping Condition:Blue Ice
Unit(s): 1 ml
Host name: Goat
Clone:
Isotype: IgG
Immunogen: Human complement C3
Application: FC, ICC, IE, IF, IHC-P, WB

Description

Description: Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form the mature protein, which is then further processed to generate numerous peptide products. The C3a peptide, also known as the C3a anaphylatoxin, modulates inflammation and possesses antimicrobial activity. Mutations in this gene are associated with atypical hemolytic uremic syndrome and age-related macular degeneration in human patients. [provided by RefSeq, Nov 2015]

Additional Text

Gene Name

C3

Gene ID

718

Molecular Weight

187

Uniprot ID

P01024

Purification

Unpurified

Antibody Clonality

Polyclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

For FACS: 1/100. For ICC: 1/500 For Ie: Use at an assay dependent dilution. For WB: 1/1000. Optimal dilutions/concentrations should be determined by the researcher.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.