Estrogen Receptor alpha antibody [6F11] (ready-to-use)
Catalogue Number: GTX73808-GTX
| Manufacturer: | GeneTex |
| Preservative: | 0.09% Sodium azide |
| Physical state: | Liquid |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | estrogen receptor 1 , ER , ESR , ESRA , ESTRR , Era , NR3A1 |
| Shipping Condition: | Blue Ice |
| Storage Condition: | 2-8°C |
| Unit(s): | 5 ml |
| Host name: | Mouse |
| Clone: | 6F11 |
| Isotype: | IgG1 |
| Immunogen: | Prokaryotic recombinant protein corresponding to the full-length estrogen receptor molecule. |
| Application: | IHC-P |
Description
Description: This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined. [provided by RefSeq, Mar 2014]
Additional Text
Gene ID
2099
Gene Name
ESR1
Uniprot ID
P03372
Molecular Weight
66
Purification
Unpurified
Antibody Clonality
Monoclonal
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Application Notes
IHC-P: . *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
GTX73808 Datasheet
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