Pancreatic Polypeptide antibody

Catalogue Number: GTX73873-GTX

Manufacturer:GeneTex
Preservative:0.09% Sodium azide
Physical state:Liquid
Type:Polyclonal Primary Antibody - Unconjugated
Alias:pancreatic polypeptide , PNP , PP
Shipping Condition:Blue Ice
Storage Condition:2-8°C
Unit(s): 1 ml
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: Synthetic human pancreatic polypeptide conjugated to keyhole limpet hemocyanin.
Application: IHC-P

Description

Description: This gene encodes a member of the neuropeptide Y (NPY) family of peptides. The encoded 95 aa preproprotein is synthesized in the pancreatic islets of Langerhans and proteolytically processed to generate two peptide products. These products include the active pancreatic hormone of 36 aa and an icosapeptide of unknown function. This hormone acts as a regulator of pancreatic and gastrointestinal functions and may be important in the regulation of food intake. Plasma level of this hormone has been shown to be reduced in conditions associated with increased food intake and elevated in anorexia nervosa. In addition, infusion of this hormone in obese rodents has shown to decrease weight gain. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016]

Additional Text

Molecular Weight

10

Uniprot ID

P01298

Gene Name

Ppy

Gene ID

5539

Purification

Purified

Antibody Clonality

Polyclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

IHC-P: 1:25-1:50. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.